由德州农工大学流行病学家Rebecca Fischer领导的研究团队发现，一种原因不明的慢性肾脏病（CKDu，又称中美洲肾病）正在德州蔓延。1该团队对休斯顿本·陶布医院2012-2015年间的数据进行分析，发现在Harris Health系统346例无保险或无证患者的肾衰竭病例中，有17%无法确定明确病因。1根据这一比例推算，德州每年可能有数千起急性透析就诊与CKDu有关。1该研究成果已于2025年3月发表。1
CKDu患者通常为40岁以下的中美洲或墨西哥籍体力劳动者，长期暴露在极端高温环境中。1流行病学家Jason Glaser形容他们的境况称："他们就像奥运会运动员，却依靠脏水和劣质食物生存。"1然而，防控工作面临诸多障碍。德州州长Greg Abbott在2023年6月签署法案，禁止市县条例要求在工作中提供饮水休息和其他热应激缓解措施。1美国劳工部随后删除了La Isla Network休息、遮阴和补水计划的资金。1此外，受影响人群不愿参与研究，担心被标记驱逐出境，这进一步加大了疾病监测的难度。1
A previously unrecognized kidney ailment has surfaced among young Central American and Mexican immigrant laborers in Texas, according to research led by epidemiologist Rebecca Fischer.1 The condition, known as CKDu (Chronic Kidney Disease of unknown origin), was identified in a study of patients treated at Houston's Ben Taub Hospital between 2012 and 2015, during which 17% of 346 uninsured or undocumented patients presenting with kidney failure could not be attributed to conventional causes.1 The research, published in March 2025, suggests that thousands of acute dialysis visits annually in Texas may be linked to CKDu.1
The disease predominantly affects laborers under 40 years old who have experienced prolonged exposure to extreme heat while performing manual work.1 Epidemiologist Jason Glaser characterized the plight of affected patients, stating: "They are like Olympic athletes, yet they survive on dirty water and poor food."1 Public health efforts to address the outbreak face significant obstacles, including policy barriers and the reluctance of vulnerable populations to participate in research due to fears of deportation.1 In June 2023, Texas Governor Greg Abbott signed legislation prohibiting local ordinances requiring water breaks and other heat-stress mitigation measures at work.1 Additionally, the U.S. Department of Labor withdrew funding from La Isla Network's hydration, shade, and rest program.1
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