深圳市第二人民医院(深圳大学第一附属医院)肿瘤科主任田耕带领团队,为55岁的肺癌复发患者刘女士制定了化疗联合深部热疗的个体化治疗方案1。经该方案治疗后,刘女士的肺部肿瘤病灶缩小超2厘米,患者状态明显改善1。
深部热疗被称为继手术、放疗、化疗、免疫治疗之后的第五大肿瘤治疗技术1。该技术利用肿瘤细胞耐热性差的特点,将局部温度维持在41-42℃,使肿瘤细胞不可逆损伤1。由于正常组织可耐受47℃以上高温,深部热疗能精准杀灭癌细胞并保护正常组织1。此外,深部热疗可与化疗、放疗、免疫治疗联合应用,以实现增效减毒1。
The Oncology Department of Shenzhen Second People's Hospital, also known as the First Affiliated Hospital of Shenzhen University, has successfully treated a 55-year-old patient, Ms. Liu, who suffered from recurrent lung cancer 1. A medical team led by Tian Geng, director of the department, formulated a personalized treatment plan combining chemotherapy with deep hyperthermia for the patient 1. Following the treatment, the lung tumor lesion in Ms. Liu shrank by more than 2 centimeters, and her overall health condition significantly improved 1.
Deep hyperthermia exploits the poor heat resistance of tumor cells by maintaining the local temperature between 41 and 42 degrees Celsius, causing irreversible damage to the cancer cells while protecting normal tissues, which can tolerate temperatures above 47 degrees Celsius 1. This technique can be combined with chemotherapy, radiotherapy, and immunotherapy to enhance efficacy and reduce toxicity 1. Currently, deep hyperthermia is recognized as the fifth major tumor treatment technology following surgery, radiotherapy, chemotherapy, and immunotherapy 1.
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